Manufacturing: Biotechnology Industry
The term biotechnology is a very broad term that can be associated with many industries, such as: Industrial Biotechnology, Medical Biotechnology, Marine Biotechnology, Environmental Biotechnology, Law, Ethics, Philosophy, Food Biotechnology, Biological Warfare, Bioinformatics, Desert Biotechnology.
What is Biotechnology?
Wikipedia: “any technological application that uses biological systems, living organisms or derivatives thereof, to make or modify products or processes for specific use”
What are Biopharmaceuticals?
Wikipedia: “any pharmaceutical drug product manufactured in, extracted from, or semi-synthesized from biological sources”
What is Bioprocessing?
Pharma IQ: “any process that uses complete living cells or their components to obtain desired products”
Trend: products are becoming more complex (1/2)
Biotech vs Conventional Pharma
Trend: products are becoming more complex (2/2)
The portion of Biotech products is increasing
Manufacturing Processes Overview: Biotech vs Conventional Pharma
1 – Conventional Pharma Manufacturing: chemical synthesis for drug manufacturing
2 – Biotechnology Manufacturing: bioprocessing for growth and harvest of biopharmaceuticals
3 – Extraction of natural drug products from vegetable or animal tissues
Chemical Synthesis Process Overview
Process Workflow for Dosage-Form Products
Bioprocessing Overview
Differences between Batch, Fed-Batch, Continuous Cultures Upstream Bioprocessing
Product Recovery Methods – Filtration and Chromatography
Downstream Bioprocessing
Depth Filtration removes cell debris due to size exclusion as well as contaminants and unwanted particles